Currently existing natural supplements that treat diseases of the muscular – skeletal system and joints have a common disadvantage, which is caused by the structure of cartilage and other tissues of the joint, a protracted period of treatment that is required to obtain a positive result. This circumstance was particularly taken into account with the of the new combined natural supplement ALLTHRIN®. . In addition to traditionally used glucosamine, chondroitine and MCM, ALLTHRIN® uses ingredients – such as inosine and orotates, which act as bio-stimulants and worked well in sport and traditional medicine. This new solution made it possible to increase the effectiveness of treatment due to the following impact factors (as compared to well-known brands): 1. Improve the conditions of nutrient delivery and repair materials to the places of destruction in the body. 2. Strengthen the tendon-muscular frame that supports the joint capsule. 3. Increased energy status of the body, that leads to an overall increased efficiency.