Unpleasant, often excruciating pain associated with decreased blood flow caused by mechanical obstruction, constricting orthopedic casts, or insufficient blood flow that results from injury or surgical trauma. Ischemic pain caused by occlusive arterial disease is often severe and may not be relieved, even with narcotics.
The individual with peripheral vascular disease may experience ischemic pain only while exercising because the metabolic demands for oxygen cannot be met as a result of occluded blood flow. The ischemic pain of partial arterial occlusion is not as severe as the abrupt, excruciating pain associated with complete occlusion, such as by an embolus or thrombus.